On Curaçao, we have small buses (vans) and large buses (called Konvoi). We recommend using the Konvoi. They are operated by the ABC bus company and operate in most tourist areas. Check the nearest bus stop or ask at your front desk where the bus stop is located. Ask the bus driver to drop you off at the bus stop nearest to Landhuis Chobolobo. The mansion is just a short walk from the bus stop. You can also view the routes of the busses on the ABC bus company website.
You can catch a taxi on the street of Curaçao, but it’s best to call them and order a taxi at a specific time. All the taxi drivers know Landhuis Chobolobo and Curaçao Liqueur Distillery. Make sure you discuss the price beforehand. It should be a price per kilometer. Ask your front desk for a taxi company or Google to find one.
If you're doing a tour to several locations on Curaçao, ask the taxi driver to include a visit to Landhuis Chobolobo and the Curaçao Liqueur Distillery.